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USC-OGP 2-DE database
Two-dimensional polyacrylamide gel electrophoresis database
USC-OGP 2-DE database
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Searching in 'USC-OGP 2-DE database' for entry
matching:
P47755
USC-OGP 2-DE database
:
P47755
P47755
General information about the entry
View entry in simple text format
Entry name
CAZA2_HUMAN
Primary accession number
P47755
integrated into USC-OGP 2-DE database on
January 17, 2017 (release 1)
2D Annotations were last modified on
January 17, 2017 (version 1)
General Annotations were last modified on
April 5, 2017 (version 2)
Name and origin of the protein
Description
RecName: Full=F-actin-capping protein subunit alpha-2; AltName: Full=CapZ alpha-2;.
Gene name
Name=CAPZA2
Annotated species
Homo sapiens (Human) [TaxID:
9606
]
Taxonomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]
2D GEL CHARACTERIZATION
Author 1., Author 2.
Submitted (Mar-2011) to Current
2D PAGE maps for identified proteins
How to interpret a protein
PLATELET_4-7
{PLATELET 4-7}
Homo sapiens (Human)
map experimental info
PLATELET_4-7
MAP LOCATIONS:
SPOT OGP-0457
:
pI=5.34; Mw=34480
PLATELET_5-6
{PLATELET 5-6}
Homo sapiens (Human)
map experimental info
PLATELET_5-6
MAP LOCATIONS:
SPOT OGP-0740
:
pI=5.28; Mw=35341
SPOT OGP-0744
:
pI=5.32; Mw=34904
SPOT OGP-0745
:
pI=5.47; Mw=34559
Cross-references
UniProtKB/Swiss-Prot
P47755; CAZA2_HUMAN.
2D PAGE maps for identified proteins
How to interpret a protein map
You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
Warning 1
: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
Warning 2
: the 2D PAGE map is built on demand. This may take some few seconds to be computed.
External data extracted from
UniProtKB/Swiss-Prot
Extracted from
UniProtKB/Swiss-Prot
, release:
0.0
Entry name
CAZA2_HUMAN
Primary accession number
P47755
Secondary accession number(s)
B4DG50
Sequence was last modified on
January 23, 2007 (version 3)
Annotations were last modified on
March 15, 2017 (version 156)
Name and origin of the protein
Description
RecName: Full=F-actin-capping protein subunit alpha-2; AltName: Full=CapZ alpha-2;
Gene name
Name=CAPZA2
Encoded on
Name=CAPZA2
Keywords
Acetylation
;
Actin capping
;
Actin-binding
;
Alternative splicing
;
Complete proteome
;
Direct protein sequencing
;
Phosphoprotein
;
Reference proteome
.
Copyright
Copyrighted by the UniProt Consortium, see
http://www.uniprot.org/help/license
. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL
U03269; AAA88848.1
; -; mRNA
EMBL
BT006735; AAP35381.1
; -; mRNA
EMBL
AK294409; BAG57661.1
; -; mRNA
EMBL
AC002543; AAC60382.1
; -; Genomic_DNA
EMBL
BC005338; AAH05338.1
; -; mRNA
EMBL
U03851; AAC00534.1
; -; mRNA
CCDS
CCDS5768.1; -. [P47755-1]
; .
PIR
G01229; G01229
; .
RefSeq
NP_006127.1; NM_006136.2. [P47755-1]
; .
UniGene
Hs.446123; -
; .
ProteinModelPortal
P47755; -
; .
SMR
P47755; -
; .
BioGrid
107280; 265
; .
IntAct
P47755; 231
; .
STRING
9606.ENSP00000354947; -
; .
iPTMnet
P47755; -
; .
PhosphoSitePlus
P47755; -
; .
BioMuta
CAPZA2; -
; .
DMDM
1345695; -
; .
DOSAC-COBS-2DPAGE
P47755; -
; .
OGP
P47755; -
; .
REPRODUCTION-2DPAGE
P47755; -
; .
EPD
P47755; -
; .
MaxQB
P47755; -
; .
PaxDb
P47755; -
; .
PeptideAtlas
P47755; -
; .
PRIDE
P47755; -
; .
DNASU
830; -
; .
Ensembl
ENST00000361183; ENSP00000354947
; ENSG00000198898. [P47755-1]; .
GeneID
830; -
; .
KEGG
hsa:830; -
; .
UCSC
uc003vil.4; human. [P47755-1]
; .
CTD
830; -
; .
DisGeNET
830; -
; .
GeneCards
CAPZA2; -
; .
HGNC
HGNC:1490; CAPZA2
; .
HPA
HPA007470; -
; .
HPA
HPA007643; -
; .
MIM
601571; gene
; .
neXtProt
NX_P47755; -
; .
OpenTargets
ENSG00000198898; -
; .
PharmGKB
PA26071; -
; .
eggNOG
KOG0836; Eukaryota
; .
eggNOG
ENOG410ZAWX; LUCA
; .
GeneTree
ENSGT00390000006476; -
; .
HOGENOM
HOG000036539; -
; .
HOVERGEN
HBG050810; -
; .
InParanoid
P47755; -
; .
KO
K10364; -
; .
OMA
TAMKAYV; -
; .
OrthoDB
EOG091G0KST; -
; .
PhylomeDB
P47755; -
; .
TreeFam
TF314822; -
; .
Reactome
R-HSA-879415; Advanced glycosylation endproduct receptor signaling
; .
Reactome
R-HSA-983231; Factors involved in megakaryocyte development and platelet production
; .
GeneWiki
CAPZA2; -
; .
GenomeRNAi
830; -
; .
PRO
PR:P47755; -
; .
Proteomes
UP000005640; Chromosome 7
; .
Bgee
ENSG00000198898; -
; .
CleanEx
HS_CAPZA2; -
; .
ExpressionAtlas
P47755; baseline and differential
; .
Genevisible
P47755; HS
; .
GO
GO:0015629; C:actin cytoskeleton
; TAS:ProtInc; .
GO
GO:0005903; C:brush border
; IEA:Ensembl; .
GO
GO:0030863; C:cortical cytoskeleton
; IEA:Ensembl; .
GO
GO:0005829; C:cytosol
; TAS:Reactome; .
GO
GO:0070062; C:extracellular exosome
; IDA:UniProtKB; .
GO
GO:0005576; C:extracellular region
; TAS:Reactome; .
GO
GO:0008290; C:F-actin capping protein complex
; TAS:ProtInc; .
GO
GO:0016020; C:membrane
; IEA:Ensembl; .
GO
GO:0051016; P:barbed-end actin filament capping
; IEA:InterPro; .
GO
GO:0007596; P:blood coagulation
; TAS:Reactome; .
GO
GO:0045087; P:innate immune response
; TAS:Reactome; .
GO
GO:0006928; P:movement of cell or subcellular component
; TAS:ProtInc; .
GO
GO:0006461; P:protein complex assembly
; TAS:ProtInc; .
InterPro
IPR002189; CapZ_alpha
; .
InterPro
IPR017865; F-actin_cap_asu_CS
; .
PANTHER
PTHR10653; PTHR10653
; 1; .
Pfam
PF01267; F-actin_cap_A
; 1; .
PRINTS
PR00191; FACTINCAPA
; .
PROSITE
PS00748; F_ACTIN_CAPPING_A_1
; 1; .
PROSITE
PS00749; F_ACTIN_CAPPING_A_2
; 1; .
Gateways to other related servers
The World-2DPAGE Constellation
- Entry point to the world-wide 2-DPAGE resources.
World-2DPAGE Repository
- A public repository for gel-based proteomics data linked to protein identification published in the literature.
World-2DPAGE Portal
- A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
SWISS-2DPAGE
- The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
ExPASy
- The resources web server of the
Swiss Institute of Bioinformatics
Database constructed and maintained by
Angel Garcia
, using the
Make2D-DB II
package (
ver. 3.10.2
) from the
World-2DPAGE Constellation
of the
ExPASy web server
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